■ 细胞核形变

SCIENCE：细胞核充当细胞形状变形的弹性机械转换器，并控制细胞的动态行为

■ 细胞质力学

Nature Physics：分裂过程中细胞内硬度降低和粘弹性流动性增加

■ 细胞膜动力学

Nature Physics：周期性障碍物调节膜张力传导，实现局部机械传递

■ 细胞膜动力学

巨型单层囊泡(giant unilamellar vesicles, GUVs)研究

■ 细胞相互作用

T细胞与肿瘤细胞相互作用

• Targeting ELOVL6 to disrupt c-MYC driven lipid metabolism in pancreatic cancer enhances chemosensitivity. Nature Communications (2025): https://doi.org/10.1038/s41467-025-56894-8

• Periodic Obstacles Regulate Membrane Tension Propagation to Enable Localized Mechanotransduction. Biorxiv (2025):https://doi.org/10.1101/2025.01.14.632796

• Measuring age-dependent viscoelasticity of organelles, cells and organisms with time-shared optical tweezer microrheology. Nature Nanotechnology (2025): DOI: 10.1038/s41565-024-01830-y

• Accessing activity and viscoelastic properties of artificial and living systems from passive measurement. Nature Materials (2024): https://doi.org/10.1038/s41563-024-01957-2

• A MEC-2/stomatin condensate liquid-to-solid phase transition controls neuronal mechanotransduction during touch sensing. Nature Cell Biology (2023): https://doi.org/10.1038/s41556-023-01247-0

• The laminin-keratin link shields the nucleus from mechanical deformation and signaling. Nature Materials (2023):  https://doi.org/10.1101/2022.03.01.482474

• Intracellular softening and increased viscoelastic fluidity during division. Nature Physics (2021). https://doi.org/10.1038/s41567-021-01368-z

• An asymmetric mechanical code ciphers curvature-dependent proprioceptor activity. SCIENCE ADVANCES (2021) DOI: 10.1126/sciadv.abg4617

• The force loading rate drives cell mechanosensing through both reinforcement and fluidization. Nature Communications (2021).  https://doi.org/10.1038/s41467-021-24383-3

• The nucleus measures shape changes for cellular proprioception to control dynamic cell behaviour. SCIENCE (2020) DOI: 10.1126/science.aba2644

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